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Valganciclovir

Names

[ CAS No. ]:
88110-89-8

[ Name ]:
Valganciclovir

[Synonym ]:
O-acetoxy ganciclovir
Valganciclovir|
6H-Purin-6-one, 9-[[2-(acetyloxy)-1-(hydroxymethyl)ethoxy]methyl]-2-amino-1,9-dihydro-
2-(2-amino-1,6 dihydro-6-oxo-purine-9-yl)-methoxy-3 acetoxy-1-propanol
2-[(2-Amino-6-oxo-1,6-dihydro-9H-purin-9-yl)methoxy]-3-hydroxypropyl acetate
2-[(2-Amino-6-oxo-3,6-dihydro-9H-purin-9-yl)methoxy]-3-hydroxypropyl acetate
T56 BN DN FVM INJ B1OY1Q1OV1 HZ
ganciclovir monoacetate
9-<(1-acetoxy-2-hydroxymethyl)ethoxymethyl>guanine
Ganciclovir Mono-O-acetate
CS-0950
HY-A0032
T56 BN DN FN HNJ D1OY1Q1OV1 GZ IQ
9-[[2-(Acetyloxy)-1-(hydroxymethyl)ethoxy]methyl]-2-amino-1,9-dihydro-6H-purin-6-one

Biological Activity

[Description]:

Ganciclovir mono-O-acetate is a derivative of Ganciclovir. Ganciclovir, a nucleoside analogue, is an orally active antiviral agent with activity against CMV[1].

[Related Catalog]:

Research Areas >> Infection
Signaling Pathways >> Others >> Others

[In Vitro]

Ganciclovir mono-o-acetate is a mono-O-acetate ester of Ganciclovir.

[References]

[1]. Faulds D, et al. Ganciclovir. A review of its antiviral activity, pharmacokinetic properties and therapeutic efficacy in cytomegalovirus infections. Drugs. 1990;39(4):597-638.

Chemical & Physical Properties

[ Density]:
1.7±0.1 g/cm3

[ Boiling Point ]:
607.8ºC at 760 mmHg

[ Melting Point ]:
194-197ºC

[ Molecular Formula ]:
C11H15N5O5

[ Molecular Weight ]:
297.267

[ Flash Point ]:
321.4ºC

[ Exact Mass ]:
297.107330

[ PSA ]:
145.35000

[ LogP ]:
-1.50

[ Index of Refraction ]:
1.692

Synthetic Route

Precursor & DownStream


Related Compounds