METANEPHRINEHYDROCHLORIDE

Names

[ CAS No. ]:
881-95-8

[ Name ]:
METANEPHRINEHYDROCHLORIDE

[Synonym ]:
4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-2-methoxyphenol hydrochloride (1:1)
Benzenemethanol, 4-hydroxy-3-methoxy-α-[(methylamino)methyl]-, (αR)-, hydrochloride (1:1)
dl-m-o-methylepinephrine hydrochloride

Chemical & Physical Properties

[ Boiling Point ]:
378.8ºC at 760 mmHg

[ Melting Point ]:
180-182ºC

[ Molecular Formula ]:
C₁₀H₁₆ClNO₃

[ Molecular Weight ]:
233.692

[ Flash Point ]:
182.9ºC

[ Exact Mass ]:
233.081863

[ PSA ]:
61.72000

[ LogP ]:
1.84650

[ Storage condition ]:
-20°C

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DA4798000

CHEMICAL NAME :: Benzenemethanol, 4-hydroxy-3-methoxy-alpha-((methylamino)methyl)-, hydrochloride, (+-)-

CAS REGISTRY NUMBER :: 881-95-8

LAST UPDATED :: 199412

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C10-H15-N-O3.Cl-H

MOLECULAR WEIGHT :: 233.72

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 840 mg/kg/42D-I

TOXIC EFFECTS :: Cardiac - other changes Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Biochemical - Metabolism (Intermediary) - lipids including transport

REFERENCE :: TXAPA9 Toxicology and Applied Pharmacology. (Academic Press, Inc., 1 E. First St., Duluth, MN 55802) V.1- 1959- Volume(issue)/page/year: 25,315,1973

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
26-36

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2922509090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2922509090

[ Summary ]:
2922509090. other amino-alcohol-phenols, amino-acid-phenols and other amino-compounds with oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

Articles

An artificial neural network for membrane-bound catechol-O-methyltransferase biosynthesis with Pichia pastoris methanol-induced cultures.

Microb. Cell Fact. 14 , 113, (2015)

Membrane proteins are important drug targets in many human diseases and gathering structural information regarding these proteins encourages the pharmaceutical industry to develop new molecules using ...

Related Compounds

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