Olmesartan medoxomil impurity C

Names

[ Name ]:
Olmesartan medoxomil impurity C

[Synonym ]:
UNII-227N84S103
Dehydro Olmesartan Medoxomil
olmesartan medoxomil dehydrate

Biological Activity

[Description]:

Olmesartan medoxomil impurity C is an Olmesartan medoxomil impurity. Olmesartan medoxomil is a potent and selective angiotensin AT1 receptor inhibitor with IC50 of 66.2 μM.

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> Angiotensin Receptor

Research Areas >> Metabolic Disease

[References]

[1]. Senda A, et al. Effects of Angiotensin II Receptor Blockers on Metabolism of Arachidonic Acid via CYP2C8. Biol Pharm Bull. 2015;38(12):1975-9.

[2]. Shah S, et al. Simultaneous Quantitative Analysis of Olmesartan Medoxomil and Amlodipine Besylate in Plasma by High-performance Liquid Chromatography Technique. J Young Pharm. 2012 Apr;4(2):88-94.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₉H₂₈N₆O₅

[ Molecular Weight ]:
540.57000

[ Exact Mass ]:
540.21200

[ PSA ]:
141.93000

[ LogP ]:
4.97570

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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