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Millewanin G

Names

[ CAS No. ]:
874303-33-0

[ Name ]:
Millewanin G

[Synonym ]:
3-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-6-(2-hydroxy-3-methyl-3-buten-1-yl)-8-(3-methyl-2-buten-1-yl)-4H-chromen-4-one
4H-1-Benzopyran-4-one, 3-(3,4-dihydroxyphenyl)-5,7-dihydroxy-6-(2-hydroxy-3-methyl-3-buten-1-yl)-8-(3-methyl-2-buten-1-yl)-

Biological Activity

[Description]:

Millewanin G is a prenylated isoflavonoid with antiestrogenic activity (IC50=29 μM). Millewanin G can be isolated from the leaves of M. pachycarpa cultivated in Japan[1].

[Related Catalog]:

Signaling Pathways >> Others >> Estrogen Receptor/ERR
Research Areas >> Endocrinology

[Target]

IC50: 29 μM (Estrogen Receptor)


[References]

[1]. Ito C, et al. Isoflavonoids with antiestrogenic activity from Millettia pachycarpa. J Nat Prod. 2006 Jan;69(1):138-41.  

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
711.9±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C25H26O7

[ Molecular Weight ]:
438.47

[ Flash Point ]:
244.2±26.4 °C

[ Exact Mass ]:
438.167847

[ PSA ]:
131.36000

[ LogP ]:
5.31

[ Vapour Pressure ]:
0.0±2.4 mmHg at 25°C

[ Index of Refraction ]:
1.660

Safety Information

[ Hazard Codes ]:
Xi


Related Compounds

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