m-PEG5-Boc

Names

[ Name ]:
m-PEG5-Boc

[Synonym ]:
MFCD28976703
2,5,8,11,14-Pentaoxaheptadecan-17-oic acid, 1,1-dimethylethyl ester
2-Methyl-2-propanyl 2,5,8,11,14-pentaoxaheptadecan-17-oate

Biological Activity

[Description]:

m-PEG5-Boc is a PEG-based PROTAC linker can be used in the synthesis of PROTACs[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> PROTAC >> PROTAC Linker

[Target]

PEGs

[In Vitro]

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

[References]

[1]. Balasingam Radhakrishnan, et al. Fatty acid formulations for oral delivery of proteins and peptides, and uses thereof. US20060018874A1.

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
390.8±32.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₆H₃₂O₇

[ Molecular Weight ]:
336.421

[ Flash Point ]:
166.2±25.2 °C

[ Exact Mass ]:
336.214813

[ LogP ]:
-0.02

[ Vapour Pressure ]:
0.0±0.9 mmHg at 25°C

[ Index of Refraction ]:
1.441

Related Compounds

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