8-hydroxy-dpat hydrobromide
Names
[ CAS No. ]:
87394-87-4
[ Name ]:
8-hydroxy-dpat hydrobromide
[Synonym ]:
Naphtho[2,3-b]furan-4,9-dione,8-hydroxy-2-(1-hydroxyethyl)
(+)-8-hydroxy-2-(di-n-propylamino)tetralin*HBr
MFCD00055158
5-hydrohymethylfurfural
(+)-8-hydroxy-2(di-N-propylamino)-tetralin hydrobromide
(+)-8-hydroxy-dipropyl-aminotetralin hydrobromide
8-hydroxy-2-(1-hydroxyethyl)naphtho[2,3-b]furan-4,9-dione
(+)-8-OH-DPAT hydrobromide
Chemical & Physical Properties
[ Melting Point ]:
221.5-222 °C
[ Molecular Formula ]:
C16H26BrNO
[ Molecular Weight ]:
328.28800
[ Exact Mass ]:
327.12000
[ PSA ]:
23.47000
[ LogP ]:
4.32960
MSDS
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S26-S36
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
Articles
Nat. Chem. Biol. 3(5) , 268-273, (2007)
The identification of self-renewing and multipotent neural stem cells (NSCs) in the mammalian brain holds promise for the treatment of neurological diseases and has yielded new insight into brain canc...
5-HT1D receptor inhibits renal sympathetic neurotransmission by nitric oxide pathway in anesthetized rats.Vascul. Pharmacol. 72 , 172-80, (2015)
Although serotonin has been shown to inhibit peripheral sympathetic outflow, serotonin regulation on renal sympathetic outflow has not yet been elucidated. This study investigated which 5-HT receptor ...
Pharmacological evidence that 5-HT1D activation induces renal vasodilation by NO pathway in rats.Clin. Exp. Pharmacol. Physiol. 42 , 640-7, (2015)
5-HT is a powerful vasoconstrictor substance in renal vasculature (mainly by 5-HT₂ activation). Nevertheless, 5-HT is notable for its dual cardiovascular effects, producing both vasodilator and vasoco...