INCB13739

Names

[ Name ]:
INCB13739

[Synonym ]:
INCB13739

Biological Activity

[Description]:

11β-HSD1-IN-12 is a 11β-HSD1 inhibitor (Example 21 in reference patent). 11β-HSD1 regenerates active glucocorticoids from inactive forms and is important in regulating intracellular glucocorticoid concentration. 11β-HSD1-IN-12 can be used in the research of obesity and metabolic syndrome[1].

[Related Catalog]:

Research Areas >> Metabolic Disease

[References]

[1]. Wenqing Yao, et al. N-substituted piperidines and their use as pharrmaceuticals. Patent. US20060004049A1.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₉H₂₇ClN₂O₃S

[ Molecular Weight ]:
398.94700

[ Exact Mass ]:
398.14300

[ PSA ]:
78.35000

[ LogP ]:
5.35700

Related Compounds

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