SPA-S 510

Names

[ Name ]:
SPA-S 510

[Synonym ]:
3-Phenyl-2-propenoic Acid 2-Methyl-3-((2-pyridinylamino)carbonyl)-2H-1,2-benzothiazin-4-yl Ester S,S-Dioxide
2-Methyl-1,1-dioxido-3-(2-pyridinylcarbamoyl)-2H-1,2-benzothiazin-4-yl (2E)-3-phenylacrylate
SPA-S-51O
SPA-S-510
SPA-S 510
4-Hydroxy-2-methyl-N-2-pyridyl-2H-1,2-benzothiazine-3-carboxamide 1,1-Dioxide Cinnamate (Ester)
Cinnoxicam
Piroxicam cinnamate
Piroxicam cinnamic acid ester
2-methyl-1,1-dioxido-3-(pyridin-2-ylcarbamoyl)-2H-1,2-benzothiazin-4-yl (2E)-3-phenylprop-2-enoate
2-Propenoic acid, 3-phenyl-, 2-methyl-1,1-dioxido-3-[(2-pyridinylamino)carbonyl]-2H-1,2-benzothiazin-4-yl ester, (2E)-
Piroxicam cinnamate (USAN)
Sinartrol

Biological Activity

[Description]:

Piroxicam cinnamate (Cinnoxicam) is a cyclooxygenase (COX) inhibitor, with anti-inflammatory activity. Piroxicam cinnamate is stable under gastric conditions, can be used for inflammatory-degenerative osteoarticular diseases, rheumatic disorders, and varicocele (VC) associated oligoasthenospermia research[1][2][4].

[Related Catalog]:

Research Areas >> Inflammation/Immunology

Signaling Pathways >> Immunology/Inflammation >> COX

[In Vivo]

Piroxicam cinnamate decreases plantar edema induced by egg's white in the rat's hind paw[3].

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Melting Point ]:
261ºC

[ Molecular Formula ]:
C₂₄H₁₉N₃O₅S

[ Molecular Weight ]:
461.490

[ Exact Mass ]:
461.104553

[ PSA ]:
114.05000

[ LogP ]:
3.96

[ Index of Refraction ]:
1.697

Related Compounds

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