(R)-(-)-Etodolac
Names
[ CAS No. ]:
87226-41-3
[ Name ]:
(R)-(-)-Etodolac
[Synonym ]:
(S)-ethyl-9,10-difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido-[1,2,3-de]-1,4-benzoxazine-6-carboxylate
(-)-ethyl-9,10-difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido [1,2,3-de]-1,4-benzoxazine-6-carboxylate
(R)-etodolac
(S)-Ethyl 9,10-difluoro-3-methyl-7-oxo-3,7-dihydro-2H-[1,4]oxazino[2,3,4-ij]quinoline-6-carboxylate
(R)-1,8-diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indole-1-acetic acid
R-(-)-etodolic acid
(S)-9,10-Difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic Acid Ethyl Ester
ethyl (S)-(-)-9,10-difluoro-2,3-dihydro-3-methyl-7-oxo-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylate
[14C]-(R)-Etodolac
(-)-etodolac
Chemical & Physical Properties
[ Density]:
1.165g/cm3
[ Boiling Point ]:
452.6ºC at 760 mmHg
[ Molecular Formula ]:
C17H21NO3
[ Molecular Weight ]:
287.35400
[ Flash Point ]:
227.5ºC
[ Exact Mass ]:
287.15200
[ PSA ]:
62.32000
[ LogP ]:
3.38300
[ Index of Refraction ]:
1.581
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UQ0360010
- CHEMICAL NAME :
- Pyrano(3,4-b)indole-1-acetic acid, 1,3,4,9-tetrahydro-1,8-diethyl-, (R)-
- CAS REGISTRY NUMBER :
- 87226-41-3
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 1
- MOLECULAR FORMULA :
- C17-H21-N-O3
- MOLECULAR WEIGHT :
- 287.39
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 327 mg/kg
- TOXIC EFFECTS :
- Behavioral - tremor Behavioral - convulsions or effect on seizure threshold Nutritional and Gross Metabolic - body temperature decrease
- REFERENCE :
- OYYAA2 Oyo Yakuri. Pharmacometrics. (Oyo Yakuri Kenkyukai, CPO Box 180, Sendai 980-91, Japan) V.1- 1967- Volume(issue)/page/year: 40,737,1990