LY 81067

Names

[ Name ]:
LY 81067

Biological Activity

[Description]:

LY 81067 is a new anticonvulsive compound that effectively protects against pentylenetetrazole- and picrotoxin-induced convulsions in mice. It exerts its anticonvulsant effects by binding to or near picrotoxin binding sites.

[References]

1. Wong DT, Threlkeld PG, Bymaster FP, Squires RF. Saturable binding of 35S-t-butylbicyclophosphorothionate to the sites linked to the GABA receptor and the interaction with GABAergic agents. Life Sci. 1984 Feb 27;34(9):853-60. PubMed PMID: 6321873.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₂H₂₄N₄O

[ Molecular Weight ]:
360.45

Related Compounds

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