Spiradoline mesylate

Names

[ Name ]:
Spiradoline mesylate

[Synonym ]:
2-(3,4-Dichlorophenyl)-N-methyl-N-[(5R,7S,8S)-7-(1-pyrrolidinyl)-1-oxaspiro[4.5]dec-8-yl]acetamide methanesulfonate (1:1)
MFCD00153876
(±)-(5α,7α,8β)-3,4-Dichloro-N-methyl-N-[7-(1-pyrrolidinyl)-1-oxaspiro[4.5]dec-8-yl]benzeneacetamide mesylate salt
Benzeneacetamide, 3,4-dichloro-N-methyl-N-[(5R,7S,8S)-7-(1-pyrrolidinyl)-1-oxaspiro[4.5]dec-8-yl]-, methanesulfonate (1:1)
Spiradoline mesylate
Spiradoline mesylate salt

Biological Activity

[Description]:

Spiradoline (U 62066) is a potent, highly selective κ-opioid agonist that has analgesic diuretic and antitussive effects. Pain Phase 2 Discontinued

[References]

References 1. Peters GR, et al. J Pharmacol Exp Ther. 1987 Jan;240(1):128-31. 2. Kamei J, et al. Eur J Pharmacol. 1990 Oct 9;187(2):281-6. 3. Kunihara M, et al. Life Sci. 1989;45(13):1191-8. View Related Products by Target Opioid Receptor Pain

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₃H₃₄Cl₂N₂O₅S

[ Molecular Weight ]:
521.497

[ Exact Mass ]:
520.156555

Related Compounds

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