4-Amino-1-Boc-piperidine

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
277.3±33.0 °C at 760 mmHg

[ Melting Point ]:
50°C

[ Molecular Formula ]:
C₁₀H₂₀N₂O₂

[ Molecular Weight ]:
200.278

[ Flash Point ]:
121.5±25.4 °C

[ Exact Mass ]:
200.152481

[ PSA ]:
55.56000

[ LogP ]:
0.67

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.484

Click to get detail MSDS

[ Symbol ]:

GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H302-H315-H318-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ Hazard Codes ]:
Xn:Harmful

[ Risk Phrases ]:
R20/21/22;R36/37/38

[ Safety Phrases ]:
S26-S36/37/39-S22-S222636/37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
2

[ HS Code ]:
2933399090

Click to get detail synthetic route

Precursor

DownStream

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Annulation of primary amines to piperazines and diazaspirocycles utilizing alpha-methyl benzyl resin.

J. Comb. Chem. 8 , 132, (2006)

The microwave-assisted solid-phase synthesis of piperazines, 3,9-diazaspiro[5.5]undecanes and 2,9-diazaspiro[5.5]undecanes is reported. The synthesis relies on the direct annulation of primary amines ...

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