Evocalcet

Names

[ Name ]:
Evocalcet

[Synonym ]:
E58MLH082P
evocalcet
{4-[(3S)-3-{[(1R)-1-(1-Naphthyl)ethyl]amino}-1-pyrrolidinyl]phenyl}acetic acid
Benzeneacetic acid, 4-[(3S)-3-[[(1R)-1-(1-naphthalenyl)ethyl]amino]-1-pyrrolidinyl]-

Biological Activity

[Description]:

Evocalcet has an activating effect on calcium sensing receptor (CaSR) extracted from patent WO 2017061621 A1, compound A.

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> CaSR

Research Areas >> Metabolic Disease

[Target]

CaSR[1]

[References]

[1]. Tanimura, Shinji, et al. Pharmaceutical composition containing aryl alkyl amine compound. WO 2017061621 A1.

[Related Small Molecules]

NPS-2143 | Strontium Ranelate | Calcium-Sensing Receptor Antagonists I | SB-423562

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
594.4±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₄H₂₆N₂O₂

[ Molecular Weight ]:
374.475

[ Flash Point ]:
313.3±30.1 °C

[ Exact Mass ]:
374.199432

[ LogP ]:
4.00

[ Vapour Pressure ]:
0.0±1.8 mmHg at 25°C

[ Index of Refraction ]:
1.666