POLYDEOXYADENYLIC-THYMIDYLIC ACID SODIUM SALT

Names

[ Name ]:
POLYDEOXYADENYLIC-THYMIDYLIC ACID SODIUM SALT

[Synonym ]:
MFCD00131964

Biological Activity

[Description]:

Polydeoxyadenylic-thymidylic acid sodium is a synthetic DNA polymer. Polydeoxyadenylic-thymidylic acid sodium can be used to determine the activity of bound and free ribonucleic acid polymerase. Polydeoxyadenylic-thymidylic acid sodium can be used for the research of cancer and virus infection[1].

[Related Catalog]:

Research Areas >> Cancer

Research Areas >> Infection

Signaling Pathways >> Others >> Others

[References]

[1]. Graham EM, et al. Effect of gestational age and hypoxia on activity of ribonucleic acid polymerase in fetal guinea pig brain. Am J Obstet Gynecol. 2001 Mar;184(4):736-42.

Chemical & Physical Properties

No Any Chemical & Physical Properties

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

Articles

Unbiased modifier screen reveals that signal strength determines the regulatory role murine TLR9 plays in autoantibody production.

J. Immunol. 194(8) , 3675-86, (2015)

The autoimmune disease systemic lupus erythematosus has a complex environmental and multifactorial genetic basis. Genome-wide association studies have recently identified numerous disease-associated p...

PATZ1 Is a DNA Damage-Responsive Transcription Factor That Inhibits p53 Function.

Mol. Cell. Biol. 35(10) , 1741-53, (2015)

Insults to cellular health cause p53 protein accumulation, and loss of p53 function leads to tumorigenesis. Thus, p53 has to be tightly controlled. Here we report that the BTB/POZ domain transcription...

Conformational variability of poly(dA-dT).poly(dA-dT) and some other deoxyribonucleic acids includes a novel type of double helix.

J. Biomol. Struct. Dyn. 3 , 67-83, (1985)

The article reviews data indicating that poly(dA-dT).poly(dA-dT) is able of adopting three distinct double helical structures in solution, of which only the A form conforms to classical notions. The o...

Related Compounds

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