diethyl trichloromethylphosphonate
Names
[ CAS No. ]:
866-23-9
[ Name ]:
diethyl trichloromethylphosphonate
[Synonym ]:
trichloromethanephosphonic acid diethyl ester
diethyl 1,1,1-trichloromethylphosphonate
Methanephosphonic acid,trichloro-,diethyl ester
Phosphonic acid,trichloromethyl-,diethyl ester
MFCD00013666
Ro 3-0658
diethyl trichloromethanephosphonate
Chemical & Physical Properties
[ Density]:
1.362 g/mL at 25ºC(lit.)
[ Boiling Point ]:
126ºC (0.3 torr)
[ Molecular Formula ]:
C5H10Cl3O3P
[ Molecular Weight ]:
255.46400
[ Flash Point ]:
>230 °F
[ Exact Mass ]:
253.94300
[ PSA ]:
45.34000
[ LogP ]:
3.58020
[ Appearance of Characters ]:
Liquid
[ Index of Refraction ]:
n20/D 1.463(lit.)
[ Storage condition ]:
2-8°C
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TA0988000
- CHEMICAL NAME :
- Phosphonic acid, trichloromethyl-, diethyl ester
- CAS REGISTRY NUMBER :
- 866-23-9
- BEILSTEIN REFERENCE NO. :
- 1210640
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C5-H10-Cl3-O3-P
- MOLECULAR WEIGHT :
- 255.47
- WISWESSER LINE NOTATION :
- GXGGPO&O2&O2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD - Lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >250 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- NCNSA6 National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. (Washington, DC) Volume(issue)/page/year: 5,20,1953
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 720 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FATOBP Farmakologiya i Toksikologiya (Kiev). Pharmacology and Toxicology. (Kievskii Nauchno- Issledovatel'skii Institut Farmakologii i Toksikologii, Kiev, USSR) No.1- 1964- Volume(issue)/page/year: 10,121,1975
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 320 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#00008
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
Xi: Irritant;
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
26-36
[ RIDADR ]:
UN3278
[ WGK Germany ]:
3
[ RTECS ]:
TA0988000
[ Packaging Group ]:
III
[ Hazard Class ]:
6.1
[ HS Code ]:
2931900090
Synthetic Route
Customs
[ HS Code ]: 2931900090
[ Summary ]:
2931900090. other organo-inorganic compounds. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0%
Articles
Tetrahedron 38 , 1457, (1982)
Addition of diethyl trichloromethylphosphonate to olefins catalysed by copper complexes. Villemin D, et al.
Tetrahedron Lett. 35(21) , 3537-38, (1994)
Photochemical type I and II elimination reactions of dialkyl (trichloromethyl) phosphonates. Suzuki N, et al.
Bull. Chem. Soc. Jpn. 53(5) , 1421-24, (1980)