<Suppliers Price>

Tauro-Obeticholic acid

Names

[ CAS No. ]:
863239-61-6

[ Name ]:
Tauro-Obeticholic acid

Biological Activity

[Description]:

Tauro-Obeticholic acid is an active metabolite of Obeticholic acid. Obeticholic acid is an orally bioavailable farnesoid-X receptor (FXR) agonist[1].

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> FXR
Research Areas >> Inflammation/Immunology

[In Vitro]

Obeticholic acid is conjugated with taurine in the liver to form Tauro-obeticholic acid, which is secreted into bile. Microorganisms in the ileum and colon can deconjugate Tauro-obeticholic acid, converting it into the parent drug, which may then be reabsorbed or excreted in faeces[1].

[References]

[1]. Markham A, et al. Obeticholic Acid: First Global Approval. Drugs. 2016 Aug;76(12):1221-6.

Chemical & Physical Properties

[ Molecular Formula ]:
C28H49NO6S

[ Molecular Weight ]:
527.76

Related Compounds