Patentiflorin A

Names

[ Name ]:
Patentiflorin A

Biological Activity

[Description]:

Patentiflorin A is a potent, broadspectrum HIV-1 inhibitor. Patentiflorin A also inhibits HIV drug-resistant strains[1].

[Related Catalog]:

Signaling Pathways >> Anti-infection >> HIV

Research Areas >> Infection

[Target]

HIV-1

[In Vitro]

Patentiflorin A shows inhibition activity with IC50 values of 32, 31, 30, 32, 108, 61 and 47 nM against Bal: M-Tropic, 89.6: Dual-Tropic, SF162: M-Tropic, Lav.04: T-Tropic, HIV-1LAV, HIV-11617-1 and HIV-1N119, respectively[1].

[References]

[1]. Zhang HJ, et al. Potent Inhibitor of Drug-Resistant HIV-1 Strains Identified from the Medicinal Plant Justicia gendarussa. J Nat Prod. 2017 Jun 23;80(6):1798-1807.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₇H₂₆O₁₁

[ Molecular Weight ]:
526.49

Related Compounds

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