(-)-Haplomyrfolin

Names

[ Name ]:
(-)-Haplomyrfolin

[Synonym ]:
(3S,4S)-3-Benzo[1,3]dioxol-5-ylmethyl-4-(4-hydroxy-3-methoxy-benzyl)-dihydro-furan-2-one
(+/-)-haplomyrfolin

Biological Activity

[Description]:

(-)-Haplomyrfolin is a natural lignan with anticancer effects[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[In Vitro]

(-)-Haplomyrfolin (compound 8) 对人肺腺癌细胞（A549 细胞）显示出显着的细胞毒性，IC50 值为 0.273 μM[1]。

[References]

[1]. Li-Ping Liu, et al. Topoisomerase II inhibitors from the roots of Stellera chamaejasme L. Bioorg Med Chem. 2014 Aug 1;22(15):4198-203.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₀H₂₀O₆

[ Molecular Weight ]:
356.36900

[ Exact Mass ]:
356.12600

[ PSA ]:
74.22000

[ LogP ]:
2.70390

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.