1-(4-HYDROXYPHENYL)-5-METHYLPYRIDIN-2(1H)-ONE

Names

[ Name ]:
1-(4-HYDROXYPHENYL)-5-METHYLPYRIDIN-2(1H)-ONE

[Synonym ]:
MFCD07369446

Biological Activity

[Description]:

Hydronidone is a pyridine derivative and an antifibrotic agent for hepatic fibrosis[1].

[References]

[1]. Liu Y, et al. Tolerability and Pharmacokinetics of Hydronidone, an Antifibrotic Agent for Hepatic Fibrosis, after Single and Multiple Doses in Healthy Subjects: an Open-Label, Randomized, Dose-Escalating, First-in-Human Study. Eur J Drug Metab Pharmacokinet. 2017;42(1):37-48.

Chemical & Physical Properties

[ Melting Point ]:
161-162 °C

[ Molecular Formula ]:
C₁₂H₁₁NO₂

[ Molecular Weight ]:
201.22100

[ Exact Mass ]:
201.07900

[ PSA ]:
42.23000

[ LogP ]:
1.85150

Safety Information

[ HS Code ]:
2933399090

Customs

[ HS Code ]: 2933399090

[ Summary ]:
2933399090. other compounds containing an unfused pyridine ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%