N3-C2-NHSester

Names

[ CAS No. ]:
850180-76-6

[ Name ]:
N3-C2-NHSester

[Synonym ]:
MFCD24452814

Biological Activity

[Description]:

N3-C2-NHS ester is a noncleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

[Related Catalog]:

Research Areas >> Cancer

[Target]

Noncleavable


[References]

[1]. Gregson SJ, et al. Pyrrolobenzodiazepine Dimer Antibody-Drug Conjugates: Synthesis and Evaluation of Noncleavable Drug-Linkers. J Med Chem. 2017 Dec 14;60(23):9490-9507.

Chemical & Physical Properties

[ Molecular Formula ]:
C7H8N4O4

[ Molecular Weight ]:
212.16

Related Compounds