Blepharotriol

Names

[ CAS No. ]:
849590-42-7

[ Name ]:
Blepharotriol

[Synonym ]:
Methyl (2R,4aS,6aS,12bR,14aS,14bR)-9,10,11-trihydroxy-2,4a,6a,12b,14a-pentamethyl-8-oxo-1,2,3,4,4a,5,6,6a,8,12b,13,14,14a,14b-tetradecahydro-2-picenecarboxylate
2-Picenecarboxylic acid, 1,2,3,4,4a,5,6,6a,8,12b,13,14,14a,14b-tetradecahydro-9,10,11-trihydroxy-2,4a,6a,12b,14a-pentamethyl-8-oxo-, methyl ester, (2R,4aS,6aS,12bR,14aS,14bR)-

Biological Activity

[Description]:

Blepharotriol is a phenolic triterpene that can be found in Maytenus blepharodes. Blepharotriol shows antimicrobial activity with a MIC value of 8-4 µg/ml for Bacillus subtilis. Blepharotriol shows cytotoxic activity with IC50s of 12.2, >20, >20 µM for HeLa, Hep-2, Vero cells, respectively[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Others >> Others

[References]

[1]. Félix M.Rodríguez, et al. New phenolic triterpenes from Maytenus blepharodes. Semisynthesis of 6-deoxoblepharodol from pristimerin. Tetrahedron. 2005, 61 (9): 2513-2519.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
641.0±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C29H38O6

[ Molecular Weight ]:
482.608

[ Flash Point ]:
208.5±25.0 °C

[ Exact Mass ]:
482.266846

[ LogP ]:
7.02

[ Vapour Pressure ]:
0.0±2.0 mmHg at 25°C

[ Index of Refraction ]:
1.617

Related Compounds

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