Lup-20(29)-en-28-oic acid

Names

[ Name ]:
Lup-20(29)-en-28-oic acid

[Synonym ]:
(3β)-3-{[6-Deoxy-α-L-mannopyranosyl-(1->2)-[β-D-glucopyranosyl-(1->4)]-α-L-arabinopyranosyl]oxy}-23-hydroxylup-20(29)-en-28-oic acid
Pulsatilla saponin D
LUP-20(29)-EN-28-OIC ACID
Pulsatillasaponin D
Pulsatillasaponin
Lup-20(29)-en-28-oic acid, 3-[[O-6-deoxy-α-L-mannopyranosyl-(1->2)-O-[β-D-glucopyranosyl-(1->4)]-α-L-arabinopyranosyl]oxy]-23-hydroxy-, (3β)-

Biological Activity

[Description]:

Lup-20(29)-en-28-oic acid, a triterpenoid saponins of Pulsatilla koreana Root, possesses anti-inflammatory and anti-tumor effect[1][2].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

[References]

[1]. Wei Li, et al. Triterpenoid saponins of Pulsatilla koreana root have inhibition effects of tumor necrosis factor-α secretion in lipopolysaccharide-induced RAW264.7 cells. Chem Pharm Bull (Tokyo). 2013;61(4):471-6.

[2]. Seong-Cheol Bang, et al. Antitumor activity of Pulsatilla koreana saponins and their structure-activity relationship. Chem Pharm Bull (Tokyo). 2005 Nov;53(11):1451-4.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
994.3±65.0 °C at 760 mmHg

[ Melting Point ]:
250-252 ºC

[ Molecular Formula ]:
C₄₇H₇₆O₁₇

[ Molecular Weight ]:
913.096

[ Flash Point ]:
284.3±27.8 °C

[ Exact Mass ]:
912.508240

[ PSA ]:
274.75000

[ LogP ]:
5.66

[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.615

[ Water Solubility ]:
Insuluble (1.8E-3 g/L) (25 ºC)

Related Compounds

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