7,3′,5′-Trihydroxyflavanone

Names

[ Name ]:
7,3′,5′-Trihydroxyflavanone

[Synonym ]:
(2S)-2-(3,5-Dihydroxyphenyl)-2,3-dihydro-7-hydroxy-4H-1-benzopyran-4-one
4H-1-Benzopyran-4-one, 2-(3,5-dihydroxyphenyl)-2,3-dihydro-7-hydroxy-, (2S)-

Biological Activity

[Description]:

7,3′,5′-Trihydroxyflavanone, a flavanoid derivative, induces the apoptotic cell death of MCF-7 cells by increasing Bax expression level. 7,3′,5′-Trihydroxyflavanone also exhibits antioxidant activity[1][2].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis

Research Areas >> Cancer

[References]

[1]. Abdullah H, et, al. A natural compound from Hydnophytum formicarium induces apoptosis of MCF-7 cells via up-regulation of Bax. Cancer Cell Int. 2010 May 4;10:14.

[2]. Tsvetkov DE, et, al. Components of the extracts of the knot wood of Dalbergia Sissoo Linn. and their antioxidant activity. Russian Chemical Bulletin. 2019 Sep; 68:1756-1762.

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
580.1±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₅H₁₂O₅

[ Molecular Weight ]:
272.253

[ Flash Point ]:
225.8±23.6 °C

[ Exact Mass ]:
272.068481

[ LogP ]:
2.04

[ Vapour Pressure ]:
0.0±1.7 mmHg at 25°C

[ Index of Refraction ]:
1.693

Related Compounds

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