cis-4,7,10,13,16,19-Docosahexaenoic acid ethyl ester

Names

[ Name ]:
cis-4,7,10,13,16,19-Docosahexaenoic acid ethyl ester

[Synonym ]:
Ethyl (4Z,7Z,10Z,13Z,16Z,19Z)-docosa-4,7,10,13,16,19-hexaenoate
4,7,10,13,16,19-Docosahexaenoic acid, ethyl ester, (4E,7E,10E,13E,16E,19E)-
Ethyl (4E,7E,10E,13E,16E,19E)-4,7,10,13,16,19-docosahexaenoate
cis-4,7,10,13,16,19-docosahexaenoic acid ethyl ester
Ethyl (4Z,7Z,10Z,13Z,16Z,19Z)-4,7,10,13,16,19-docosahexaenoate
MFCD00056293
4,7,10,13,16,19-Docosahexaenoic acid, ethyl ester, (4Z,7Z,10Z,13Z,16Z,19Z)-
4,7,10,13,16,19-docosahexaenoic acid ethyl ester
4,7,10,13,16,19-Docosahexaenoic acid, ethyl ester

Biological Activity

[Description]:

Ethyl cis-4,7,10,13,16,19-Docosahexaenoate, the ethyl ester of Docosahexaenoate (DHA), is enriched in the ethyl ester fraction by the selective alcoholysis of fatty acid ethyl esters originating from tuna oil with lauryl alcohol.

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

[In Vitro]

Ethyl cis-4,7,10,13,16,19-Docosahexaenoate (Ethyl docosahexaenoate; E-DHA) is efficiently enriched by the selective alcoholysis of ethyl esters originating from tuna oil with lauryl alcohol using immobilized lipase[1].

[References]

[1]. Yuji Shimada, et al. Purification of ethyl docosahexaenoate by selective alcoholysis of fatty acid ethyl esters with immobilized Rhizomucor miehei lipase. J Am Oil Chem Soc. 1998 Nov, 75(11): 1565–1571.

[Related Small Molecules]

Chemical & Physical Properties

[ Density]:
0.9±0.1 g/cm3

[ Boiling Point ]:
443.5±24.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₄H₃₆O₂

[ Molecular Weight ]:
356.541

[ Flash Point ]:
102.1±21.2 °C

[ Exact Mass ]:
356.271515

[ PSA ]:
26.30000

[ LogP ]:
7.77

[ Vapour Pressure ]:
0.0±1.1 mmHg at 25°C

[ Index of Refraction ]:
1.504

[ Storage condition ]:
−20°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves

[ Hazard Codes ]:
Xi

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

Docosahexaenoic acid counteracts attenuation of CD95-induced cell death by inorganic mercury.

Toxicol. Appl. Pharmacol. 282(1) , 61-7, (2015)

In the United States the principal environmental exposure to mercury is through dietary consumption of sea food. Although the mechanism by which low levels of mercury affect the nervous system is not ...

Protective effects of prescription n-3 fatty acids against impairment of spatial cognitive learning ability in amyloid β-infused rats.

Food Funct. 2(7) , 386-94, (2011)

Deposition of amyloid β peptide (Aβ) into the brain causes cognitive impairment. We investigated whether prescription pre-administration of n-3 fatty acids improves cognitive learning ability in young...

Identification of inflammatory and proresolving lipid mediators in bone marrow and their lipidomic profiles with ovariectomy and omega-3 intake.

Am. J. Hematol. 83(6) , 437-45, (2008)

Newly described lipoxygenase (LOX)-generated lipid mediators, that is, resolvins and protectins as well as lipoxins, are both anti-inflammatory and proresolving. We aimed to determine whether these li...