LDN-76070

Names

[ Name ]:
LDN-76070

Biological Activity

[Description]:

LDN-76070 is a novel potent SMN2 modulator (EC50=8.3 uM; Emax 186%), increases SMN protein in spinal cord and brain in mice (5 mg/kg).

[References]

References 1. Rietz A, et al. J Med Chem. 2017 Jun 8;60(11):4594-4610. 2. Cherry JJ, et al. EMBO Mol Med. 2013 Jul;5(7):1103-18. View Related Products by Target SMN2 Modulator

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₈H₁₇BrFNO₄

[ Molecular Weight ]:
410.239

Related Compounds

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