Spiraprilat

Names

[ Name ]:
Spiraprilat

[Synonym ]:
Spiraprilate
SPIRAPRILAT
Spiraprilatum
UNII-QS56V5Y7EC

Biological Activity

[Description]:

Spiraprilat is a potent angiotensin-converting enzyme (ACE) inhibitor. Spiraprilat has ability to improve left ventricular (LV) function and metabolism in anesthetized open-chest dogs with acute ventricular failure (ALVF)[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease

Signaling Pathways >> Metabolic Enzyme/Protease >> Angiotensin-converting Enzyme (ACE)

[References]

[1]. Nakazawa M, et al. Effects of spiraprilat, an angiotensin-converting enzyme inhibitor, on anesthetized dogs in a new model of acute left ventricular failure. J Cardiovasc Pharmacol. 1993 Oct;22(4):585-93.

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₀H₂₆N₂O₅S₂

[ Molecular Weight ]:
438.56100

[ Exact Mass ]:
438.12800

[ PSA ]:
157.54000

[ LogP ]:
2.24110

Related Compounds

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