Flufylline
Names
[ CAS No. ]:
82190-91-8
[ Name ]:
Flufylline
[Synonym ]:
Flufyllin
Flufilina [Spanish]
1H-Purine-2,6-dione,7-(2-(4-(4-fluorobenzoyl)-1-piperidinyl)ethyl)-3,7-dihydro-1,3-dimethyl
Sgd 195 78
Flufylline
Flufyllinum [Latin]
Theophylline,7-(2-(4-(p-fluorobenzoyl)piperidino)ethyl)
7-(2-(4-(p-Fluorobenzoyl)piperidino)ethyl)theophylline
Flufylline [INN]
Chemical & Physical Properties
[ Density]:
1.39g/cm3
[ Boiling Point ]:
632.8ºC at 760 mmHg
[ Molecular Formula ]:
C21H24FN5O3
[ Molecular Weight ]:
413.44500
[ Flash Point ]:
336.5ºC
[ Exact Mass ]:
413.18600
[ PSA ]:
82.13000
[ LogP ]:
1.10560
[ Index of Refraction ]:
1.662
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- XH5624000
- CHEMICAL NAME :
- Theophylline, 7-(2-(4-(p-fluorobenzoyl)piperidino)ethyl)-
- CAS REGISTRY NUMBER :
- 82190-91-8
- LAST UPDATED :
- 198806
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C21-H24-F-N5-O3
- MOLECULAR WEIGHT :
- 413.50
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 149 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - ptosis Behavioral - altered sleep time (including change in righting reflex) Behavioral - ataxia
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 34,1,1984
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 12 mg/kg
- TOXIC EFFECTS :
- Sense Organs and Special Senses (Eye) - ptosis Behavioral - altered sleep time (including change in righting reflex) Behavioral - ataxia
- REFERENCE :
- ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 34,1,1984