Tetradecanedioic acid

Names

[ CAS No. ]:
821-38-5

[ Name ]:
Tetradecanedioic acid

[Synonym ]:
1,14-tetradecanedioic acid
EINECS 212-476-9
Tetradecanedioic acid
MFCD00002743

Biological Activity

[Description]:

Tetradecanedioic acid is an endogenous metabolite and belongs to the class of organic compounds known as long-chain fatty acids. Tetradecanedioic acid can act as a candidate biomarker for organic anion-transporting polypeptide mediated drug-drug interactions [1].

[Related Catalog]:

Research Areas >> Metabolic Disease

[References]

[1]. Santockyte R, et al. LC-MS/MS bioanalysis of plasma 1, 14-tetradecanedioic acid and 1, 16-hexadecanedioic acid as candidate biomarkers for organic anion-transporting polypeptide mediated drug-drug interactions. Bioanalysis. 2018 Sep 1;10(18):1473-1485.

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
434.1±18.0 °C at 760 mmHg

[ Melting Point ]:
124-127 °C(lit.)

[ Molecular Formula ]:
C₁₄H₂₆O₄

[ Molecular Weight ]:
258.354

[ Flash Point ]:
230.5±17.7 °C

[ Exact Mass ]:
258.183105

[ PSA ]:
74.60000

[ LogP ]:
3.99

[ Vapour Pressure ]:
0.0±2.2 mmHg at 25°C

[ Index of Refraction ]:
1.475

[ Water Solubility ]:
SLIGHTLY SOLUBLE

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H319-H335

[ Precautionary Statements ]:
P261-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2917190090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2917190090

[ Summary ]:
2917190090 acyclic polycarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

Chemical diagnosis of Lesch-Nyhan syndrome using gas chromatography-mass spectrometry detection.

J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 792(1) , 123-30, (2003)

Lesch-Nyhan syndrome (LNS) is caused by a severe deficiency of hypoxanthine-guanine phosphoribosyltransferase (HPRT) and clinically characterized by self-injurious behavior and nephrolithiasis; the la...

Biopterin level in peripheral blood cells as a marker for hemopoietic cell proliferation during leukemia and polycythemia vera.

Blut 44(4) , 231-40, (1982)

Using the Crithidia assay 3.0 ng biopterin/ml blood was found, of which one third was present in the plasma. The erythrocyte fraction comprised 1.7 ng and the buffy coat 0.33 ng. After Ficoll separati...