DIETHYLAMINE, N-NITROSO-2,2,2-TRIFLUORO-
Names
[ CAS No. ]:
82018-90-4
[ Name ]:
DIETHYLAMINE, N-NITROSO-2,2,2-TRIFLUORO-
[Synonym ]:
N-Nitroso-2,2,2-trifluorodiethylamine
N-ethyl-2,2,2-trifluoro-N-nitrosoethanamine
DIETHYLAMINE,N-NITROSO-2,2,2-TRIFLUORO
Chemical & Physical Properties
[ Density]:
1.27g/cm3
[ Boiling Point ]:
154.6ºC at 760 mmHg
[ Molecular Formula ]:
C4H7F3N2O
[ Molecular Weight ]:
156.10600
[ Flash Point ]:
47.3ºC
[ Exact Mass ]:
156.05100
[ PSA ]:
32.67000
[ LogP ]:
1.55200
[ Index of Refraction ]:
1.385
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- IA3535000
- CHEMICAL NAME :
- Diethylamine, N-nitroso-2,2,2-trifluoro-
- CAS REGISTRY NUMBER :
- 82018-90-4
- LAST UPDATED :
- 199410
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C4-H7-F3-N2-O
- MOLECULAR WEIGHT :
- 156.13
- WISWESSER LINE NOTATION :
- ONN2&1XFFF
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 960 mg/kg
- TOXIC EFFECTS :
- Lungs, Thorax, or Respiration - chronic pulmonary edema Gastrointestinal - other changes Liver - hepatitis (hepatocellular necrosis), diffuse
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 945 mg/kg/63W-I
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Sense Organs and Special Senses (Olfaction) - tumors Gastrointestinal - tumors
- TYPE OF TEST :
- TD - Toxic dose (other than lowest)
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1305 mg/kg/44W-I
- TOXIC EFFECTS :
- Tumorigenic - Carcinogenic by RTECS criteria Sense Organs and Special Senses (Olfaction) - tumors Gastrointestinal - tumors
MUTATION DATA
- TYPE OF TEST :
- Mutation in microorganisms
- TEST SYSTEM :
- Bacteria - Salmonella typhimurium
- DOSE/DURATION :
- 20 umol/plate
- REFERENCE :
- CRNGDP Carcinogenesis (London). (Oxford Univ. Press, Pinkhill House, Southfield Road, Eynsham, Oxford OX8 1JJ, UK) V.1- 1980- Volume(issue)/page/year: 3,155,1982