Sarcosinamide chloroethylnitrosourea
Names
[ CAS No. ]:
81965-43-7
[ Name ]:
Sarcosinamide chloroethylnitrosourea
[Synonym ]:
Sarcosinamide chloroethylnitrosourea
2-Chloroethyl-3-sarcosinamide-1-nitrosourea
Sarmustine
Sarcnu
Chemical & Physical Properties
[ Density]:
1.45g/cm3
[ Boiling Point ]:
378.1ºC at 760 mmHg
[ Molecular Formula ]:
C6H11ClN4O3
[ Molecular Weight ]:
222.63000
[ Flash Point ]:
182.5ºC
[ Exact Mass ]:
222.05200
[ PSA ]:
96.07000
[ LogP ]:
0.44600
[ Index of Refraction ]:
1.569
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- YS4552800
- CHEMICAL NAME :
- Urea, 1-(carbamoylmethyl)-3-(2-chloroethyl)-1-methyl-3-nitr oso-
- CAS REGISTRY NUMBER :
- 81965-43-7
- LAST UPDATED :
- 198909
- DATA ITEMS CITED :
- 2
- MOLECULAR FORMULA :
- C6-H11-Cl-N4-O3
- MOLECULAR WEIGHT :
- 222.66
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 392 mg/kg
- TOXIC EFFECTS :
- Tumorigenic - active as anti-cancer agent
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 25,829,1982
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intravenous
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 427 mg/kg
- TOXIC EFFECTS :
- Tumorigenic - active as anti-cancer agent
- REFERENCE :
- JMCMAR Journal of Medicinal Chemistry. (American Chemical Soc., Distribution Office Dept. 223, POB POB 57136, West End Stn., Washington, DC 20037) V.6- 1963- Volume(issue)/page/year: 25,829,1982