Xamoterol

Names

[ Name ]:
Xamoterol

[Synonym ]:
XAMOTEROL FUMARATE
N-(2-((2-hydroxy-3-(4-hydroxyphenoxy)propyl)amino)ethyl)-4-morpholinecarboxamide

Biological Activity

[Description]:

Xamoterol is a selective and potent agonist of beta1-adrenergic receptor. Xamoterol has the potential for the research of arrhythmogenesis. Xamoterol has the potential for the investigating the relationship between β1-adrenergic stimulation and IKr[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease

Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor

[References]

[1]. Wang S, et al. β1-adrenergic regulation of rapid component of delayed rectifier K+ currents in guinea-pig cardiac myocytes. Mol Med Rep. 2014;9(5):1923-1928.

Chemical & Physical Properties

[ Density]:
1.265g/cm3

[ Boiling Point ]:
651.4ºC at 760 mmHg

[ Molecular Formula ]:
C₂₀H₂₉N₃O₉

[ Molecular Weight ]:
455.45900

[ Flash Point ]:
347.7ºC

[ Exact Mass ]:
455.19000

[ PSA ]:
177.89000

[ LogP ]:
0.19480

[ Appearance of Characters ]:
solid | white

[ Index of Refraction ]:
1.571

[ Water Solubility ]:
H2O: 10 mg/mL at 60 °C, soluble

Safety Information

[ Safety Phrases ]:
22-24/25

[ WGK Germany ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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