Imiloxan hydrochloride

Names

[ Name ]:
Imiloxan hydrochloride

[Synonym ]:
imiloxan hydrochloride
2-(2,3-dihydro-1,4-benzodioxin-2ylmethyl)-1-ethyl-1H-imidazole hydrochloride
1-ethyl-2-[(1,4-benzodioxan-2-yl)methyl]imidazole hydrochloride
(1-ethyl-2-imidazoyl)methyl-1,4-benzodioxan hydrochloride
2-[(2,3-dihydro-1,4-benzodioxin-2yl)methyl]-1-ethyl-1H-imidazole hydrochloride
1-Ethyl-2-(1,4-benzodioxan-2-ylmethyl)imidazole hydrochloride
IMILOXAN HYDROCHLORIDE

Biological Activity

[Description]:

Imiloxan hydrochloride is a potent and selective alpha 2B-adrenoceptor antagonist. Imiloxan hydrochloride has the potential for acute kidney injury research[1][2].

[Related Catalog]:

Signaling Pathways >> GPCR/G Protein >> Adrenergic Receptor

Research Areas >> Metabolic Disease

[References]

[1]. A D Michel, et al. Assessment of imiloxan as a selective alpha 2B-adrenoceptor antagonist. Br J Pharmacol. 1990 Mar;99(3):560-4.

[2]. Takaomi Shimokawa, et al. Renoprotective effect of yohimbine on ischaemia/reperfusion-induced acute kidney injury through α2C-adrenoceptors in rats. Eur J Pharmacol. 2016 Jun 15;781:36-44.

Chemical & Physical Properties

[ Molecular Formula ]:
C₁₄H₁₇ClN₂O₂

[ Molecular Weight ]:
280.75

[ Exact Mass ]:
280.09800

[ PSA ]:
36.28000

[ LogP ]:
3.08750

Related Compounds

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