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Lenampicillin hydrochloride

Names

[ CAS No. ]:
80734-02-7

[ Name ]:
Lenampicillin hydrochloride

[Synonym ]:
lenampicillin hydrochloride
Lenampicillin hydrochloride (JP16)
Valacillin (TN)
Lenampicillin (hydrochloride)

Biological Activity

[Description]:

Lenampicillin (hydrochloride) is the efficient prodrug of ampicillin (ABPC ) in terms of the enhancement of absorption and decrease of side effects.In vivo : The intestinal absorption of LAPC is satisfactory in view of the urinary excretion of metabolites, accounting for 93% of dose in human, 74% in dogs and 55% in rats, respectively.

[Related Catalog]:

Signaling Pathways >> Anti-infection >> Bacterial
Research Areas >> Cancer

[References]

[1]. Awata N et al. [Metabolism of lenampicillin hydrochloride. II. Metabolism of promoiety]. Jpn J Antibiot. 1985 Jul;38(7):1785-93.

[2]. Awata N et al. [Metabolism of lenampicillin hydrochloride. I. Metabolism of ampicillin structure]. Jpn J Antibiot. 1985 Jul;38(7):1776-84.


[Related Small Molecules]

Puromycin 2HCl | Geneticin | Tunicamycin | Hygromycin B | Salinomycin | Avibactam sodium | Neomycin sulfate | Vaborbactam | Methicillin SodiuM | Rifampicin | Metronidazole | Carbenicillin disodium | Ceftazidime | Eravacycline dihydrochloride | cefotaxime sodium

Chemical & Physical Properties

[ Boiling Point ]:
717.4ºC at 760 mmHg

[ Molecular Formula ]:
C21H24ClN3O7S

[ Molecular Weight ]:
497.95

[ Flash Point ]:
387.7ºC

[ PSA ]:
170.38000

[ LogP ]:
1.86060

[ Storage condition ]:
2-8℃

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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