Schinifoline

Names

[ Name ]:
Schinifoline

[Synonym ]:
4(1H)-Quinolinone,2-heptyl-1-methyl
3-heptyl-2-methylisoquinolin-1(2H)-one
2-Heptyl-1-methyl-4(1H)-quinolinone
1-methyl-2-heptyl-4(1H)-quinolone
4(1H)-Quinolinone, 2-heptyl-1-methyl-
Schinifoline
N-methyl-2-heptyl-4-quinolone
1-Methyl-2-heptyl-4(1H)-quinolinone

Biological Activity

[Description]:

Schinifoline, a 4-quinolinone derivative isolated from Zanthoxylum schinifolium Sieb, improves radiosensitizing effect, and effects cell cycle and apoptotic-inducing effects in cancer [1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[References]

[1]. Wang CF, et al. Radiosensitizing effect of schinifoline from Zanthoxylum schinifolium Sieb et Zucc on human non-small cell lung cancer A549 cells: a preliminary in vitro investigation. Molecules. 2014 Dec 1;19(12):20128-38.

Chemical & Physical Properties

[ Density]:
1.0±0.1 g/cm3

[ Boiling Point ]:
362.6±42.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₇H₂₃NO

[ Molecular Weight ]:
257.371

[ Flash Point ]:
124.0±17.3 °C

[ Exact Mass ]:
257.177979

[ PSA ]:
22.00000

[ LogP ]:
5.03

[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C

[ Index of Refraction ]:
1.531

Safety Information

[ Hazard Codes ]:
Xi

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Related Compounds

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