euphornin

Names

[ Name ]:
euphornin

[Synonym ]:
Benzoic acid (6E,12E)-(1S,2S,3aR,4S,5S,9R,11R,13aS)-4,9,11-triacetoxy-3a-hydroxy-2,5,8,8,12-pentamethyl-2,3,3a,4,5,8,9,10,11,13a-decahydro-1H-cyclopentacyclododecen-1-yl ester

Biological Activity

[Description]:

Euphornin is a anticaner agent, that can be isolated from E. helioscopia. Euphornin induces apoptosis via caspase-mediated pathways. Euphornin induces cell cycle arrest by increasing the level of the phospho-CDK1 (Tyr15) protein[1].

[Related Catalog]:

Signaling Pathways >> Apoptosis >> Apoptosis

Research Areas >> Cancer

Signaling Pathways >> Apoptosis >> Caspase

[References]

[1]. Li XQ, et al. Euphornin reduces proliferation of human cervical adenocarcinoma HeLa cells through induction of apoptosis and G2/M cell cycle arrest. Onco Targets Ther. 2018 Jul 27;11:4395-4405.

Chemical & Physical Properties

[ Molecular Formula ]:
C₃₃H₄₄O₉

[ Molecular Weight ]:
584.70

[ Exact Mass ]:
584.29900

[ PSA ]:
125.43000

[ LogP ]:
4.96270

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.