ProtopluMericin A

Names

[ Name ]:
ProtopluMericin A

[Synonym ]:
Spiro[cyclopenta[c]pyran-7(1H),2'(5'H)-furan]-4-carboxylic acid, 1-(hexopyranosyloxy)-4'-[(1S)-1-[[(2E)-3-[4-(hexopyranosyloxy)phenyl]-1-oxo-2-propen-1-yl]oxy]ethyl]-4a,7a-dihydro-5'-oxo-, methyl ester, (1S,4aS,7R,7aS)-
Methyl (1S,4aS,7R,7aS)-1-(hexopyranosyloxy)-4'-[(1S)-1-({(2E)-3-[4-(hexopyranosyloxy)phenyl]-2-propenoyl}oxy)ethyl]-5'-oxo-4a,7a-dihydro-1H,5'H-spiro[cyclopenta[c]pyran-7,2'-furan]-4-carboxylate

Biological Activity

[Description]:

Protoplumericin A is a bioactive ingredient of Plumeria obtusa L. attenuates. Protoplumericin A mitigated lipopolysaccharide (LPS) -induced acute lung injury in mice. Protoplumericin A can be used to study the LPS-induced anti-inflammatory effect [1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Inflammation/Immunology

[References]

[1]. Eloutify YT, El-Shiekh RA, Ibrahim KM, Hamed AR, Al-Karmalawy AA, ShokryAA, Ahmed YH, Avula B, Katragunta K, Khan IA, Meselhy MR. Bioactive fractionfrom Plumeria obtusa L. attenuates LPS-induced acute lung injury in miceand inflammation in RAW 264.7 macrophages: LC/QToF-MS and moleculardocking. Inflammopharmacology. 2023 Apr;31(2):859-875.

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
1040.3±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C₃₆H₄₂O₁₉

[ Molecular Weight ]:
778.707

[ Flash Point ]:
322.5±27.8 °C

[ Exact Mass ]:
778.232056

[ PSA ]:
286.89000

[ LogP ]:
-4.76

[ Vapour Pressure ]:
0.0±0.3 mmHg at 25°C

[ Index of Refraction ]:
1.677

Precursor & DownStream

Precursor

DownStream

Related Compounds

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