Curcuma oil
Names
[ CAS No. ]:
8024-37-1
[ Name ]:
Curcuma oil
[Synonym ]:
(1E,6E)-1,7-Bis(4-hydroxy-3-methoxyphenyl)-1,6-heptadiene-3,5-dio ne
Chemical & Physical Properties
[ Density]:
1.279 g/cm3
[ Boiling Point ]:
591.4ºC at 760 mmHg
[ Melting Point ]:
183ºC
[ Molecular Formula ]:
C21H20O6
[ Molecular Weight ]:
368.38000
[ Flash Point ]:
208.9ºC
[ Exact Mass ]:
368.12600
[ PSA ]:
93.06000
[ LogP ]:
3.36990
[ Index of Refraction ]:
1.642
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- GS3774080
- CHEMICAL NAME :
- Curcuma oil
- CAS REGISTRY NUMBER :
- 8024-37-1
- LAST UPDATED :
- 199701
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >5 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- >5 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 27300 mg/kg/13W-C
- TOXIC EFFECTS :
- Liver - changes in liver weight Blood - other changes
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 13650 mg/kg/13W-C
- TOXIC EFFECTS :
- Liver - changes in liver weight
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 72800 mg/kg/2Y-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Reproductive - Tumorigenic effects - other reproductive system tumors
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 437 gm/kg/2Y-C
- TOXIC EFFECTS :
- Tumorigenic - equivocal tumorigenic agent by RTECS criteria Gastrointestinal - tumors Liver - tumors
MUTATION DATA
- TYPE OF TEST :
- Cytogenetic analysis
- TEST SYSTEM :
- Mammal - species unspecified Cells - not otherwise specified
- DOSE/DURATION :
- 10 mg/L/4H
- REFERENCE :
- FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 14,9,1976
Safety Information
[ HS Code ]:
3203001990
Customs
[ HS Code ]: 3203001990