<Suppliers Price>

SirReal1

Names

[ CAS No. ]:
801227-82-7

[ Name ]:
SirReal1

[Synonym ]:
N-(5-benzyl-1,3-thiazol-2-yl)-2-[(4,6-dimethylpyrimidin-2-yl)sulfanyl]acetamide
Acetamide, 2-[(4,6-dimethyl-2-pyrimidinyl)thio]-N-[5-(phenylmethyl)-2-thiazolyl]-
N-(5-Benzyl-1,3-thiazol-2-yl)-2-[(4,6-dimethyl-2-pyrimidinyl)sulfanyl]acetamide

Biological Activity

[Description]:

A novel potent, selective Sirt2 inhibitor with IC50 of 3.745 uM; displays no inhibitory activity against Sirt1 and Sirt 3 (IC50>100 uM).

[References]

References 1. Schiedel M, et al. Angew Chem Int Ed Engl. 2016 Feb 5;55(6):2252-6. View Related Products by Target Sirtuin

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Molecular Formula ]:
C18H18N4OS2

[ Molecular Weight ]:
370.492

[ Exact Mass ]:
370.092194

[ LogP ]:
4.60

[ Index of Refraction ]:
1.661

Related Compounds