Loflucarban

Names

[ CAS No. ]:
790-69-2

[ Name ]:
Loflucarban

[Synonym ]:
Loflucarban
Loflucarbanum [Latin]
Loflucarbanum
Fluonilid
Fluonilide
3,5-Dichloro-4'-fluorothiocarbanilide
Fluoro-4-dichloro-3',5'-thiocarbanilide

Biological Activity

[Description]:

Loflucarban (Fluonilid) is a potent antimycotic agent. Loflucarban can be used for the research of the ear infections[1].

[Related Catalog]:

Research Areas >> Infection

Signaling Pathways >> Anti-infection >> Fungal

[In Vitro]

One hundred-and-eighty-six fungi were isolated from one hundred-and-eighty cases diagnosed as otomycosis. They comprise 59 species of 26 genera of moulds, and 2 genera of yeasts. Fluonilid shows the MIC ranged from > 100 μg/ml to 1 μg/ml for the majority of tested fungi[1].

[References]

[1]. Maher A, et al. Otomycosis: an experimental evaluation of six antimycotic agents. J Laryngol Otol. 1982;96(3):205-213.

Chemical & Physical Properties

[ Density]:
1.531g/cm3

[ Boiling Point ]:
395ºC at 760 mmHg

[ Molecular Formula ]:
C₁₃H₉Cl₂FN₂S

[ Molecular Weight ]:
315.19300

[ Flash Point ]:
192.7ºC

[ Exact Mass ]:
313.98500

[ PSA ]:
56.15000

[ LogP ]:
5.08740

[ Index of Refraction ]:
1.729

[ Storage condition ]:
-20℃

Loflucarban

Names

Biological Activity

Chemical & Physical Properties

Related Compounds