dimethisterone
Names
[ CAS No. ]:
79-64-1
[ Name ]:
dimethisterone
[Synonym ]:
Secrosteron
Dimethisterone
Dimethisteron
Dimethisterone anhydrous
6a,21-dimethylethisterone
Lutogan
Chemical & Physical Properties
[ Density]:
1.11g/cm3
[ Boiling Point ]:
479ºC at 760 mmHg
[ Melting Point ]:
102°
[ Molecular Formula ]:
C23H32O2
[ Molecular Weight ]:
340.49900
[ Flash Point ]:
203.5ºC
[ Exact Mass ]:
340.24000
[ PSA ]:
37.30000
[ LogP ]:
4.51870
[ Index of Refraction ]:
1.566
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- BV8510000
- CHEMICAL NAME :
- Androst-4-en-3-one, 17-beta-hydroxy-6-alpha-methyl-17-(1-propynyl)-
- CAS REGISTRY NUMBER :
- 79-64-1
- LAST UPDATED :
- 199510
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C23-H32-O2
- MOLECULAR WEIGHT :
- 340.55
- WISWESSER LINE NOTATION :
- L E5 B666 OV MUTJ A1 E1 FQ F1UU2 L1 -A&L -B&AEF
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 100 mg/kg
- SEX/DURATION :
- female 17-20 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - urogenital system
- REFERENCE :
- ECJPAE Endocrinologia Japonica. (Japan Pub. Trading Co., Ltd., POB 5030, Tokyo International, Tokyo, Japan) V.1- 1954- Volume(issue)/page/year: 24,77,1977
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 175 mg/kg
- SEX/DURATION :
- female 15-21 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Specific Developmental Abnormalities - urogenital system
- REFERENCE :
- ACENA7 Acta Endocrinologica (Copenhagen). (Periodica, Skolegade 12 E, DK-2500 Valby, Denmark) V.1- 1948- Volume(issue)/page/year: 38,128,1961
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 70 mg/kg
- SEX/DURATION :
- female 14 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Maternal Effects - ovaries, fallopian tubes Reproductive - Fertility - other measures of fertility
- REFERENCE :
- CCPTAY Contraception. (Geron-X, Inc., POB 1108, Los Altos, CA 94022) V.1- 1970- Volume(issue)/page/year: 5,57,1972
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 28 mg/kg
- SEX/DURATION :
- female 14 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Maternal Effects - uterus, cervix, vagina
- REFERENCE :
- CCPTAY Contraception. (Geron-X, Inc., POB 1108, Los Altos, CA 94022) V.1- 1970- Volume(issue)/page/year: 5,57,1972 *** REVIEWS *** IARC Cancer Review:Animal Inadequate Evidence IMEMDT IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man. (WHO Publications Centre USA, 49 Sheridan Ave., Albany, NY 12210) V.1- 1972- Volume(issue)/page/year: 21,377,1979