AZ-2

Names

[ Name ]:
AZ-2

Biological Activity

[Description]:

AZ-2 is a small molecule inducer of ABCA1 and apoE that act through indirect activation of the LXR pathway, shows purinergic receptor P2X7 antagonist activity; upregulates ABCA1 across multiple CNS cell types, including human astrocytes, pericytes, and microglia, through an indirect LXR mechanism and that also independently inhibit P2X7 receptor activity.

[References]

References 1. Fan J, et al. J Lipid Res. 2018 May;59(5):830-842. View Related Products by Target P2X Receptor

Chemical & Physical Properties

[ Molecular Formula ]:
C₂₄H₃₂ClN₃O₂

[ Molecular Weight ]:
429.989

Related Compounds

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