1-[2-(dimethylamino)ethyl]-3-(2,6-dimethylphenyl)-1-propan-2-ylurea,hydrochloride

Names

[ CAS No. ]:
78372-06-2

[ Name ]:
1-[2-(dimethylamino)ethyl]-3-(2,6-dimethylphenyl)-1-propan-2-ylurea,hydrochloride

[Synonym ]:
c 3215

Chemical & Physical Properties

[ Boiling Point ]:
417.2ºC at 760 mmHg

[ Molecular Formula ]:
C₁₆H₂₈ClN₃O

[ Molecular Weight ]:
313.86600

[ Flash Point ]:
206.1ºC

[ Exact Mass ]:
313.19200

[ PSA ]:
39.07000

[ LogP ]:
3.92290

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: YS9965000

CHEMICAL NAME :: Urea, 1-(2-(dimethylamino)ethyl)-1-isopropyl-3-(2,6-xylyl)- , hydrochloride

CAS REGISTRY NUMBER :: 78372-06-2

LAST UPDATED :: 199012

DATA ITEMS CITED :: 3

MOLECULAR FORMULA :: C16-H27-N3-O.Cl-H

MOLECULAR WEIGHT :: 313.92

WISWESSER LINE NOTATION :: 1N1&2NY1&1&VMR B1 F1 &GH

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 8,664,1958 ** ACUTE TOXICITY DATA **

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 41 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 8,664,1958

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Subcutaneous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 57500 ug/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: ARZNAD Arzneimittel-Forschung. Drug Research. (Editio Cantor Verlag, Postfach 1255, W-7960 Aulendorf, Fed. Rep. Ger.) V.1- 1951- Volume(issue)/page/year: 8,664,1958