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N1-ACETYLSPERMINE TRIHYDROCHLORIDE

Names

[ CAS No. ]:
77928-70-2

[ Name ]:
N1-ACETYLSPERMINE TRIHYDROCHLORIDE

[Synonym ]:
MFCD00083219

Biological Activity

[Description]:

N1-Acetylspermine trihydrochloride is an endogenous metabolite present in Urine that can be used for the research of Leukemia[1][2].

[Related Catalog]:

Research Areas >> Cancer

[In Vitro]

Endogenous metabolites is defined as those that are annotated by Kyoto Encyclopedia of Genes and Genomes as substrates or products of the ~1900 metabolic enzymes encoded in our genome. It is clear in the body of literature that there are documented toxic properties for many of these metabolites[1].

[References]

[1]. Lee SH, et al. Polyamine profiles in the urine of patients with leukemia. Cancer Lett. 1998 Jan 9;122(1-2):1-8.  

[2]. Lee N, et al. Endogenous toxic metabolites and implications in cancer therapy. Oncogene. 2020 Aug;39(35):5709-5720.  

Chemical & Physical Properties

[ Molecular Formula ]:
C12H31Cl3N4O

[ Molecular Weight ]:
353.76

[ Exact Mass ]:
244.22600

[ PSA ]:
82.67000

[ LogP ]:
2.14320

[ Storage condition ]:
2-8°C

MSDS

Safety Information

[ Hazard Codes ]:
Xi: Irritant;

[ Risk Phrases ]:
36/37/38

[ Safety Phrases ]:
26-36


Related Compounds