(S)-2-Phenylpropanoic acid

Names

[ Name ]:
(S)-2-Phenylpropanoic acid

[Synonym ]:
(S)-(+)-2-Phenylpropionic Acid
(R)-(-)-α-Methylphenylacetic acid
UNII:3YF5O2136L
(-)-hydratropic acid
(2R)-2-phenylpropionic acid
(R)-(−)-2-Phenylpropionic acid
Benzeneacetic acid, α-methyl-, (αR)-
Benzeneacetic acid, α-methyl-, (αS)-
S-(+)-2-phenylpropionic acid
(R)-(-)-phenylpropionic acid
(R)-2-phenylpropanoic acid
(R)-hydratropic acid
(R)-(−)-Hydratropic acid
(2S)-2-phenylpropionic acid
Benzeneacetic acid, α-methyl-, (R)-
(S)-2-phenylpropanic acid
2-PHENYLPROPIONIC ACID, (+)-
Benzeneacetic acid, α-methyl-, (S)-
2-PHENYLPROPIONIC ACID, (-)-
(S)-hydratropic acid
(2R)-2-Phenylpropanoic acid
(S)-(+)-α-Methylphenylacetic acid
R-2-phenylpropionic acid
(2S)-2-Phenylpropanoic acid
(+)-hydratropic acid
MFCD00063139

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
261.0±0.0 °C at 760 mmHg

[ Melting Point ]:
29-30 °C(lit.)

[ Molecular Formula ]:
C₉H₁₀O₂

[ Molecular Weight ]:
150.174

[ Flash Point ]:
154.3±13.9 °C

[ Exact Mass ]:
150.068085

[ PSA ]:
37.30000

[ LogP ]:
1.85

[ Vapour Pressure ]:
0.0±0.5 mmHg at 25°C

[ Index of Refraction ]:
1.539

MSDS

Click to get detail MSDS

Safety Information

[ Symbol ]:

GHS07

[ Signal Word ]:
Warning

[ Hazard Statements ]:
H315-H317-H319-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ Hazard Codes ]:
Xi:Irritant;

[ Risk Phrases ]:
R36/37/38

[ Safety Phrases ]:
S26-S36-S37/39

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
2916399090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2916399090

[ Summary ]:
2916399090 other aromatic monocarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

Articles

Production of S-(+)-2-phenylpropionic acid from (R,S)-2-phenylpropionitrile by the combination of nitrile hydratase and stereoselective amidase in Rhodococcus equi TG328.

Appl. Microbiol. Biotechnol. 39(6) , 720-5, (1993)

A new soil isolate, tentatively identified as Rhodococcus equi TG328, was found to be effective in the production of S-(+)-2-phenylpropionic acid from (R,S)-2-phenylpropionitrile. The conversion is ca...

Stereoselective metabolism of 2-phenylpropionic acid in rat. I. In vitro studies on the stereoselective isomerization and glucuronidation of 2-phenylpropionic acid.

Drug Metab. Dispos. 15(4) , 529-34, (1987)

Optical isomerization of 2-phenylpropionic acid (hydratropic acid, HTA) was studied in the organs of male rat in vitro. (R)-(-)-HTA was not isomerized by rat liver homogenate even after the addition o...

Substrate specificity and enantioselectivity of arylcarboxylic acid glucuronidation.

Drug Metab. Dispos. 16(4) , 627-34, (1988)

A general and sensitive HPLC method using a precolumn switching system was developed for the separation and quantification of the individual diastereoisomeric glucuronides of the 2-phenylpropionic aci...