INT Formazan

[ Density]:
1.6±0.1 g/cm3

[ Boiling Point ]:
564.9±60.0 °C at 760 mmHg

[ Melting Point ]:
187ºC (dec.)(lit.)

[ Molecular Formula ]:
C₁₉H₁₄IN₅O₂

[ Molecular Weight ]:
471.251

[ Flash Point ]:
295.5±32.9 °C

[ Exact Mass ]:
471.019196

[ PSA ]:
94.93000

[ LogP ]:
7.74

[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C

[ Index of Refraction ]:
1.693

Click to get detail MSDS

[ Symbol ]:

GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H334

[ Precautionary Statements ]:
P261-P342 + P311

[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Faceshields;Gloves

[ Hazard Codes ]:
Xi

[ Risk Phrases ]:
43

[ Safety Phrases ]:
22-24/25-36/37

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2928000090

Click to get detail synthetic route

Precursor

DownStream

[ HS Code ]: 2928000090

[ Summary ]:
2928000090 other organic derivatives of hydrazine or of hydroxylamine VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:20.0%

PKCalpha tumor suppression in the intestine is associated with transcriptional and translational inhibition of cyclin D1.

Exp. Cell Res. 315(8) , 1415-28, (2009)

Alterations in PKC isozyme expression and aberrant induction of cyclin D1 are early events in intestinal tumorigenesis. Previous studies have identified cyclin D1 as a major target in the antiprolifer...

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