Dihydroberberine

Names

[ Name ]:
Dihydroberberine

[Synonym ]:
9,10-Dimethoxy-5,8-dihydro-6H-[1,3]dioxolo[4,5-g]isoquinolino[3,2-a]isoquinoline
9,10-Dimethoxy-7-methyl-6,7-dihydro-5H-[1,3]benzodioxolo[6,5,4-de]benzo[g]quinoline
5H-1,3-Benzodioxolo[6,5,4-de]benzo[g]quinoline, 6,7-dihydro-9,10-dimethoxy-7-methyl-
6H-1,3-Benzodioxolo[5,6-a]benzo[g]quinolizine, 5,8-dihydro-9,10-dimethoxy-
9,10-Dimethoxy-5,8-dihydro-6H-[1,3]dioxolo[4,5-g]isoquino[3,2-a]isoquinoline
Dihydroberberine

Biological Activity

[Description]:

Dehydrocrebanine is an alkaloid that can be isolated from the tuber and leaves of Stephania venosa. Dehydrocrebanine has in vitro anti-cancer activity[1].

[Related Catalog]:

Research Areas >> Cancer

Signaling Pathways >> Others >> Others

[References]

[1]. Makarasen A, et al. Cytotoxic and antimicrobial activities of aporphine alkaloids isolated from Stephania venosa (Blume) Spreng. Planta Med. 2011 Sep;77(13):1519-24.

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
547.6±50.0 °C at 760 mmHg

[ Molecular Formula ]:
C₂₀H₁₉NO₄

[ Molecular Weight ]:
337.37

[ Flash Point ]:
167.2±27.3 °C

[ Exact Mass ]:
337.131409

[ PSA ]:
40.16000

[ LogP ]:
4.23

[ Vapour Pressure ]:
0.0±1.5 mmHg at 25°C

[ Index of Refraction ]:
1.682

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: DE5378000

CHEMICAL NAME :: 5H-Benzo(g)-1,3-benzodioxolo(6,5,4-de)quinoline, 6,7-dihydro-9,10-dimethoxy-7-methyl-

CAS REGISTRY NUMBER :: 77784-22-6

LAST UPDATED :: 199410

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C20-H19-N-O4

MOLECULAR WEIGHT :: 337.40

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 5 ug/plate

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 240,267,1990

Safety Information

[ Hazard Codes ]:
Xi