CGS-9895
Names
[ CAS No. ]:
77779-50-1
[ Name ]:
CGS-9895
[Synonym ]:
2-(4-methoxyphenyl)-pyrazolo[4,3-c]quinolin-3-one
Cgs 9895
2-(p-methoxyphenyl)-pyrazolo-[4,3-c]quinolin-3(5H)-one
2-(4'-methoxyphenyl)-2,5-dihydropyrazolo-(4,3-c)quinolin-3-one
2,5-Dihydro-2-(4-methoxyphenyl)-3H-pyrazolo(4,3-c)quinolin-3-one
Chemical & Physical Properties
[ Density]:
1.338g/cm3
[ Boiling Point ]:
518.6ºC at 760 mmHg
[ Molecular Formula ]:
C17H13N3O2
[ Molecular Weight ]:
291.30400
[ Flash Point ]:
267.5ºC
[ Exact Mass ]:
291.10100
[ PSA ]:
59.91000
[ LogP ]:
2.87560
[ Index of Refraction ]:
1.691
MSDS
Safety Information
[ RIDADR ]:
NONH for all modes of transport
[ HS Code ]:
2933990090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2933990090
[ Summary ]:
2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%
Articles
Eur. J. Pharmacol. 263(1-2) , 141-7, (1994)
The effects of benzodiazepine receptor ligands with different intrinsic activity profiles were studied on voluntary ethanol consumption in the selectively bred alcohol-preferring AA (Alko, Alcohol) ra...
Comparison of a new class of pyrrole containing benzodiazepine ligands to the pyrazoloquinolinones CGS 9896, 9895, and 8216.Med. Chem. Res. 4(5) , 307-14, (1994)
Four pyrazoloquninolinone compounds, variations of known high affinity ligands for the GABA A/Benzodiazepine receptors (BDZRs), were synthesized and their affinities for BDZRs in cerebellum and spinal...
Benzodiazepine-induced hyperphagia: stereospecificity and antagonism by pyrazoloquinolines, CGS 9895 and CGS 9896.Psychopharmacology 89(4) , 462-6, (1986)
Non-deprived male rats were familiarized with a highly palatable diet until baseline consumption in a 30-min daily access period had stabilised. Stereospecificity of the hyperphagic effect of benzodia...