1-(2-chloroethyl)-3-[2-[2-[(2-chloroethyl-nitroso-carbamoyl)amino]ethy ldisulfanyl]ethyl]-1-nitroso-urea
Names
[ CAS No. ]:
77469-44-4
[ Name ]:
1-(2-chloroethyl)-3-[2-[2-[(2-chloroethyl-nitroso-carbamoyl)amino]ethy ldisulfanyl]ethyl]-1-nitroso-urea
[Synonym ]:
Ditiomustine
CNCC
I.C.I.G. 1325
Chemical & Physical Properties
[ Molecular Formula ]:
C10H18Cl2N6O4S2
[ Molecular Weight ]:
421.32400
[ Exact Mass ]:
420.02100
[ PSA ]:
201.14000
[ LogP ]:
2.57780
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- YT2150000
- CHEMICAL NAME :
- Urea, 1,1'-dithiodiethylenebis(3-(2-chloroethyl)-3-nitroso-
- CAS REGISTRY NUMBER :
- 77469-44-4
- LAST UPDATED :
- 199612
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C10-H18-Cl2-N6-O4-S2
- MOLECULAR WEIGHT :
- 421.36
- WISWESSER LINE NOTATION :
- ONNG2&VM2SS2MVNNO&2G
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 280 mg/kg
- TOXIC EFFECTS :
- Tumorigenic - active as anti-cancer agent
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 75 mg/kg
- TOXIC EFFECTS :
- Tumorigenic - active as anti-cancer agent
MUTATION DATA
- TYPE OF TEST :
- Mutation test systems - not otherwise specified
- TEST SYSTEM :
- Rodent - mouse Cells - not otherwise specified
- DOSE/DURATION :
- 20 mg/L
- REFERENCE :
- INSSDM INSERM Symposium. (Elsevier Science Pub. Co., Inc., 52 Vanderbilt Ave., New York, NY 10017) No.1- 1975- Volume(issue)/page/year: 19,229,1981
Synthetic Route
Related Compounds
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.