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seravschanin

Names

[ CAS No. ]:
77331-76-1

[ Name ]:
seravschanin

[Synonym ]:
Propanoic acid, 2-methyl-, (9R,10R)-9-(acetyloxy)-9,10-dihydro-8,8-dimethyl-2-oxo-2H,8H-benzo[1,2-b:3,4-b']dipyran-10-yl ester
(9R,10R)-9-Acetoxy-8,8-dimethyl-2-oxo-9,10-dihydro-2H,8H-pyrano[2,3-f]chromen-10-yl 2-methylpropanoate
(9R,10R)-9-(acetyloxy)-8,8-dimethyl-2-oxo-9,10-dihydro-2H,8H-pyrano[2,3-f]chromen-10-yl 2-methylpropanoate

Biological Activity

[Description]:

Hyuganin D (Isobocconin) is a Coumarin (HY-N0709) constituent that substantially inhibits LPS (HY-D1056)-induced NO production in mouse peritoneal macrophages[1].

[Related Catalog]:

Signaling Pathways >> Others >> Others
Research Areas >> Inflammation/Immunology

[References]

[1]. Yoshikawa M, et al. Inhibitory effects of coumarin and acetylene constituents from the roots of Angelica furcijuga on D-galactosamine/lipopolysaccharide-induced liver injury in mice and on nitric oxide production in lipopolysaccharide-activated mouse peritoneal macrophages. Bioorg Med Chem. 2006 Jan 15;14(2):456-63.  

Chemical & Physical Properties

[ Density]:
1.3±0.1 g/cm3

[ Boiling Point ]:
465.7±45.0 °C at 760 mmHg

[ Melting Point ]:
166-167℃ (ethanol )

[ Molecular Formula ]:
C20H22O7

[ Molecular Weight ]:
374.38

[ Flash Point ]:
202.5±28.8 °C

[ Exact Mass ]:
374.136566

[ PSA ]:
92.04000

[ LogP ]:
3.37

[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C

[ Index of Refraction ]:
1.564

Safety Information

[ Hazard Codes ]:
Xi

Related Compounds