croconazole

Names

[ Name ]:
croconazole

[Synonym ]:
1-[1-[2-[(3-Chlorobenzyl)oxy]phenyl]ethenyl]-1H-imidazole
1-(1H-Imidazole-1-yl)-1-[2-(3-chlorobenzyloxy)phenyl]ethene
Croconazole (Cloconazole)
Cloconazole
1-[1-(2-(3-chlorobenzyloxy)phenyl)vinyl]imidazole
1-(1-{2-[(3-chlorobenzyl)oxy]phenyl}vinyl)-1H-imidazole
Viniconazole
Pilzcin

Biological Activity

[Description]:

Croconazole is an antifungal agent containing imidazole rings. Croconazole has a unique structural feature of aryl vinyl at the imidazole ring N-1. Croconazole can be used for the identification and quantitative study of major metabolites in rat urine and bile [1].

[Related Catalog]:

Signaling Pathways >> Others >> Others

Research Areas >> Metabolic Disease

[References]

[1]. Nakano M, et al. Croconazole metabolism in rats.Xenobiotica. 1990 Apr;20(4):385-93.

Chemical & Physical Properties

[ Density]:
1.16g/cm3

[ Boiling Point ]:
501.5ºC at 760 mmHg

[ Melting Point ]:
72-73ºC

[ Molecular Formula ]:
C₁₈H₁₅ClN₂O

[ Molecular Weight ]:
310.78

[ Flash Point ]:
257.1ºC

[ Exact Mass ]:
310.08700

[ PSA ]:
27.05000

[ LogP ]:
4.63450

[ Index of Refraction ]:
1.593

Safety Information

[ HS Code ]:
2933290090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2933290090

[ Summary ]:
2933290090. other compounds containing an unfused imidazole ring (whether or not hydrogenated) in the structure. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%